Important Safety Information: SCREAM CREAM (Aminophylline, Arginine, Sildenafil) | Compounded Topical Cream

What is this?

This Important Safety Information summarizes key warnings and precautions for SCREAM CREAM, a compounded topical formulation containing aminophylline, arginine, and sildenafil. These ingredients are used to support localized blood flow and vascular response when applied topically as directed by a licensed healthcare provider. This formulation is intended for external use only.

This compounded topical cream has not been reviewed or approved by the U.S. Food and Drug Administration for safety or efficacy. It should only be used exactly as prescribed by a licensed healthcare provider. This summary does not include all available information. Always read your medication label and follow your provider’s instructions.

Most Serious Warnings

Product can cause:

• Severe allergic reactions, including rash, hives, swelling of the face, lips, or throat

• Significant local irritation, burning, or skin reactions

• Headache, dizziness, flushing, or lightheadedness

• Low blood pressure, especially in individuals sensitive to vasodilators

• Cardiovascular effects in patients with underlying heart conditions

• Potential interaction with nitrates or other medications that affect blood pressure

Compounded topical medications may carry formulation or consistency risks due to limited FDA oversight.

Who Should NOT Use This Medication

Do not use this medication if you:

• Have a known allergy to aminophylline, arginine, sildenafil, or any component of the formulation

• Are currently taking nitrates or nitric oxide donors for chest pain

• Have been advised to avoid medications that affect blood flow or blood pressure

• Have uncontrolled cardiovascular disease

• Have open wounds, irritated skin, or infections at the intended application site

Before Using SCREAM CREAM, Tell Your Healthcare Provider if You:

• Have heart disease, arrhythmias, or a history of stroke

• Have low blood pressure or episodes of dizziness or fainting

• Take medications for blood pressure, chest pain, or erectile dysfunction

• Use other topical medications in the same area

• Are pregnant, planning pregnancy, or breastfeeding

• Take prescription, over-the-counter, herbal, or recreational substances

Possible Side Effects

Common (mild to moderate):

• Local redness, warmth, or tingling at the application site

• Mild burning or itching

• Headache

• Flushing

• Dizziness

Serious (seek medical care immediately):

• Swelling of the face, lips, tongue, or throat

• Difficulty breathing

• Chest pain or irregular heartbeat

• Severe dizziness or fainting

• Persistent or worsening skin reaction

While Using This Medication

Tell your healthcare provider immediately if you:

• Develop severe skin irritation or blistering

• Experience chest pain, palpitations, or shortness of breath

• Feel faint, weak, or lightheaded

• Notice symptoms that do not improve or worsen over time

It may take some time for this medication to produce noticeable effects. Do not apply more than prescribed. Do not double doses if a dose is missed. If you miss an application, resume at your next scheduled time unless otherwise directed by your provider.

Overdose

Excessive use may increase the risk of systemic side effects such as low blood pressure, headache, flushing, or cardiovascular symptoms. If accidental overuse or ingestion occurs, seek emergency medical attention or contact Poison Control immediately.

Storage

• Store at room temperature unless otherwise directed on the pharmacy label

• Keep tightly closed and protected from excessive heat

• Keep out of reach of children and pets

Medication Disposal

Dispose of unused or expired medication according to local medication disposal guidelines. Do not flush medication or dispose of it in household drains. Contact your pharmacy for proper disposal instructions.

Provider Oversight and Order Review

This compounded medication requires review and oversight by a licensed Superior Health & Wellness provider. Dosing instructions and frequency of use must be discussed directly with your provider to ensure safety and clinical appropriateness. Orders may be adjusted based on your medical history and response to therapy.

Telemedicine Disclosure

This prescription may be issued via telemedicine. If you experience concerning or severe symptoms, contact your prescribing clinician immediately or seek emergency medical care.

Disclaimer

This summary does not include all information about SCREAM CREAM and should not replace medical guidance. Always consult your healthcare provider or pharmacist for complete safety information, potential interactions, and individualized treatment recommendations. This compounded medication has not been evaluated or approved by the FDA for safety or efficacy.