Minocycline Hydrochloride Capsules, USP | Oral Antibiotic
Important Safety Information: Minocycline Hydrochloride Capsules | Oral Tetracycline-Class Antibiotic
What is this?
This Important Safety Information summarizes key warnings and precautions for Minocycline Hydrochloride Capsules, a tetracycline-class antibiotic used to treat certain bacterial infections, including skin infections and severe acne. To reduce the development of drug-resistant bacteria and maintain effectiveness, this medication should only be used to treat infections proven or strongly suspected to be caused by bacteria . This summary does not include all available information. Always read your prescription label and follow your healthcare provider’s instructions.
Most Serious Warnings
Minocycline can cause:
Permanent tooth discoloration and enamel changes if used during pregnancy or in children under 8 years of age
Fetal harm if taken during pregnancy
Severe skin reactions, including Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Intracranial hypertension (increased pressure in the brain), which may cause headache, blurred vision, or vision loss
Clostridium difficile–associated diarrhea, which may occur during or after treatment
Severe allergic reactions, including anaphylaxis
Liver toxicity, including hepatitis and rare cases of liver failure
Who Should NOT Take Minocycline
Do not take this medication if you:
Are allergic to minocycline or other tetracycline antibiotics
Are pregnant
Are a child under 8 years of age
Before Taking Minocycline, Tell Your Healthcare Provider if You:
Have liver or kidney disease
Have a history of intracranial hypertension or severe headaches
Are taking isotretinoin, blood thinners, penicillin antibiotics, ergot medications, iron supplements, or antacids containing aluminum, calcium, or magnesium
Use oral contraceptives, as effectiveness may be reduced
Are breastfeeding, as tetracyclines pass into breast milk
Possible Side Effects
Common:
Nausea, vomiting, diarrhea
Dizziness, lightheadedness, or vertigo
Photosensitivity (increased risk of sunburn)
Serious (seek medical care immediately):
Severe or persistent headache, blurred or double vision
Watery or bloody diarrhea
Rash, hives, swelling of the face or throat, difficulty breathing
Yellowing of the skin or eyes, severe fatigue, or abdominal pain
Severe skin reactions with fever or swollen lymph nodes
While Taking Minocycline
Avoid excessive sunlight or tanning beds due to risk of severe sunburn
Take with a full glass of liquid to reduce the risk of throat irritation or ulceration
Do not skip doses and complete the full prescribed course to reduce antibiotic resistance
Pregnancy and Breastfeeding
Minocycline may harm an unborn baby and can cause permanent tooth discoloration during fetal development . It is not recommended during pregnancy or in children under 8 years of age. Tetracyclines are excreted in breast milk and may pose risks to nursing infants .
Overdose
Symptoms of overdose may include dizziness, nausea, and vomiting . If overdose is suspected, seek emergency medical attention or contact Poison Control immediately.
Missed Dosage
If you miss a dose, take it as soon as you remember. Do not double doses. Follow your provider’s instructions.
Storage
Store at 20° to 25°C (68° to 77°F)
Protect from light, moisture, and excessive heat
Keep out of reach of children
Telemedicine Disclosure
This prescription may be issued via telemedicine. If you experience severe or concerning symptoms, contact your prescribing clinician or seek emergency medical care immediately.
Disclaimer
This summary does not include all information about Minocycline Hydrochloride Capsules, USP. For full prescribing information, refer to the FDA-approved labeling . Always consult your healthcare provider or pharmacist for complete safety information, potential interactions, and individualized treatment recommendations.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch or call 1-800-FDA-1088.
