NP Thyroid® | Oral Thyroid Tablets
Important Safety Information: NP Thyroid® | Oral Thyroid Tablets
What is this?
This Important Safety Information summarizes key warnings and precautions for NP Thyroid®, a prescription oral thyroid hormone medication containing levothyroxine (T4) and liothyronine (T3). It is indicated for replacement or supplemental therapy in patients with hypothyroidism and for certain thyroid-related conditions as determined by a licensed healthcare provider. According to the manufacturer labeling, NP Thyroid is a natural preparation derived from porcine thyroid glands and is marketed as an unapproved drug product that has not been found by the FDA to be safe and effective, and its labeling has not been approved by the FDA. This summary does not include all available information. Always read your medication label and follow your provider’s instructions.
Most Serious Warnings
Product can cause:
Excess thyroid hormone levels (hyperthyroidism) leading to chest pain, rapid or irregular heartbeat, palpitations, shortness of breath, or heart attack
Worsening of angina or underlying heart disease, especially in older adults
Severe allergic reactions, including rash, hives, or swelling
Bone loss with long-term overtreatment
Life-threatening toxicity if taken in excessive doses
Thyroid hormones should not be used for weight loss. In patients with normal thyroid function, doses within the daily hormonal requirement are ineffective for weight reduction. Larger doses may produce serious or life-threatening toxicity, particularly when combined with sympathomimetic agents.
Who Should NOT Take NP Thyroid
Do not take this medication if you:
Have untreated adrenal insufficiency
Have untreated thyrotoxicosis (overactive thyroid)
Have a known hypersensitivity to thyroid hormone preparations or any ingredient in the formulation
Before Taking NP Thyroid, Tell Your Healthcare Provider if You:
Have heart disease, angina, irregular heartbeat, or high blood pressure
Have diabetes or use insulin or oral hypoglycemic medications
Take oral anticoagulants such as warfarin
Are pregnant or planning pregnancy
Are breastfeeding
Take estrogen, oral contraceptives, corticosteroids, androgens, or iodine-containing products
Take biotin or biotin-containing supplements
Have pituitary or adrenal gland disorders
Possible Side Effects
Common or related to excessive dosing:
Increased heart rate
Palpitations
Nervousness or anxiety
Heat intolerance
Sweating
Weight loss
Tremors
Insomnia
Temporary hair loss in children
Serious (seek medical care immediately):
Chest pain
Shortness of breath
Fainting
Severe rapid or irregular heartbeat
Signs of allergic reaction such as swelling of the face, lips, tongue, or throat
While Taking NP Thyroid
Tell your healthcare provider immediately if you:
Experience chest pain or worsening angina
Develop rapid or irregular heartbeat
Notice unexplained weight changes
Experience excessive sweating, nervousness, or tremors
Have changes in blood sugar control if diabetic
Pregnancy and Breastfeeding
Thyroid hormone replacement therapy should not be discontinued during pregnancy in patients with hypothyroidism. Thyroid hormones do not readily cross the placental barrier and are not associated with known serious adverse fetal effects when appropriately dosed. Minimal amounts are excreted in breast milk. Use during pregnancy and breastfeeding should remain under provider supervision.
Overdose
Symptoms of overdose may resemble hyperthyroidism and include rapid heartbeat, chest pain, tremors, nervousness, fever, sweating, vomiting, diarrhea, or confusion. If overdose is suspected, seek emergency medical care immediately or contact Poison Control.
Missed Dosage
If you miss a dose:
Take it as soon as you remember unless it is close to your next scheduled dose
Do not double the next dose
Contact your provider if you are unsure how to resume therapy
Laboratory Monitoring
Regular monitoring of TSH and thyroid hormone levels is required to ensure appropriate dosing. Biotin supplements should be stopped at least 2 days prior to thyroid function testing, as they may interfere with laboratory results.
Storage
Store in a tight container
Protect from light and moisture
Store between 59°F and 86°F (15°C–30°C)
Keep out of reach of children
Provider Oversight and Order Review
NP Thyroid dosing must be individualized based on clinical response and laboratory values. Adjustments are typically made within the first four weeks of therapy. Close monitoring is especially important in elderly patients and those with cardiovascular disease.
Telemedicine Disclosure
If prescribed via telemedicine, contact your prescribing clinician immediately if you experience concerning or severe symptoms, or seek emergency medical care.
Disclaimer
This summary does not include all information about NP Thyroid and should not replace medical guidance. Always consult your healthcare provider or pharmacist for complete safety information, potential interactions, and individualized treatment recommendations. According to the manufacturer labeling, this product has not been found by the FDA to be safe and effective and its labeling has not been approved by the FDA. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch or call 1-800-FDA-1088.
