SCREAM CREAM (Sildenafil Citrate 5% / Aminophylline 3% / L-Arginine 5% / Ergoloid Mesylate 0.123% / Pentoxifylline 2.5%) | Compounded Topical
Scream Cream is a compounded topical formulation designed to support sexual arousal and sensitivity in women when clinically appropriate. This formulation contains sildenafil citrate 5%, aminophylline 3%, L-arginine 5%, ergoloid mesylate 0.123%, and pentoxifylline 2.5%. These ingredients work together to support localized blood flow and vascular activity in external genital tissue when applied topically.
By supporting localized circulation and smooth muscle relaxation, this formulation may help enhance sensitivity and arousal response in women experiencing symptoms associated with decreased sexual responsiveness. Because the medication is applied directly to the external genital area, it is designed to act locally with the goal of minimizing systemic absorption.
This is a compounded cream formulation dispensed by a licensed compounding pharmacy. Compounded medications are not FDA-approved and have not been reviewed for safety or efficacy. Review important medication safety information.
Important Safety Information: SCREAM CREAM Vaginal Cream | Compounded Topical
(Sildenafil Citrate 5% / Aminophylline 3% / L-Arginine 5% / Ergoloid Mesylate 0.123% / Pentoxifylline 2.5%)
What is this?
This Important Safety Information summarizes key warnings and precautions for Scream Cream #1, a compounded topical vaginal cream containing sildenafil citrate, aminophylline, L-arginine, ergoloid mesylate, and pentoxifylline. This formulation is designed to increase localized blood flow to the clitoris and external genital tissue, which may support improved sensitivity, arousal response, and sexual stimulation when clinically appropriate. The medication works locally at the application site and is intended to minimize systemic absorption. This customized compounded formulation is prepared by a licensed compounding pharmacy and has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety or efficacy. Use only as directed by a licensed healthcare provider. This summary does not include all available information. Always read your prescription label and follow your provider’s instructions.
Most Serious Warnings
This product may cause serious adverse reactions in some individuals, including:
Severe allergic reactions such as rash, hives, itching, swelling of the face, lips, tongue, or throat
Difficulty breathing, chest tightness, wheezing, or severe dizziness
Blue or discolored skin tone
Severe skin irritation or hypersensitivity reactions
Pain, redness, swelling, or warmth in the legs that may indicate circulation problems
Because this medication contains multiple active compounds that influence blood flow and vascular activity, systemic effects may occur in rare cases.
Compounded medications may carry additional sterility, potency, or formulation variability risks due to limited FDA oversight.
Who Should NOT Use This Medication
Do not use this medication if you:
Have a known allergy to sildenafil, aminophylline, L-arginine, ergoloid mesylate, pentoxifylline, or any component of the formulation
Have a history of genital herpes outbreaks that may be triggered by L-arginine
Have chronic vaginal infections or severe genital irritation
Have been advised by a healthcare provider to avoid sexual activity due to a medical condition
Have serious cardiovascular disease without provider clearance
Before Using This Medication, Tell Your Healthcare Provider if You:
Have a history of cardiovascular disease, circulation disorders, or blood pressure abnormalities
Have autoimmune disorders or chronic inflammatory conditions
Have a history of genital herpes or recurrent infections
Are pregnant, planning pregnancy, or breastfeeding
Take prescription medications, over-the-counter drugs, supplements, or herbal products
Smoke, drink alcohol regularly, or use recreational drugs
Possible Side Effects
Common (mild to moderate):
Mild skin irritation, redness, or burning at the application site
Headache
Dizziness or lightheadedness
Restlessness or mild nervous system stimulation
Serious (seek medical care immediately):
Rash, hives, or severe allergic reaction
Swelling of the face, lips, tongue, or throat
Chest pain or severe dizziness
Difficulty breathing or wheezing
Severe skin reactions or painful swelling
While Using This Medication
This medication increases blood flow to the applied area but does not directly cause orgasm. If the cream is not fully absorbed before sexual activity, irritation may occur for a partner.
Tell your healthcare provider if:
Symptoms do not improve or worsen
You develop unusual irritation or discomfort
You experience new or unexpected symptoms
Missed Dose
If you miss a dose:
Apply the dose when you remember unless it is near the next scheduled application
Skip the missed dose if it is almost time for the next one
Do not apply extra medication to make up for a missed dose
Storage
Store at room temperature according to pharmacy instructions
Keep the container tightly closed
Keep out of reach of children and pets
Medication Disposal
Dispose of unused or expired medication according to local hazardous medication disposal regulations. Do not flush medication or dispose of it in household drains unless instructed. Contact your pharmacy for disposal guidance.
Provider Oversight and Order Review
This compounded medication requires prescription authorization and clinical oversight by a licensed Superior Health & Wellness provider. Treatment recommendations and dosing instructions are individualized based on patient health history and clinical assessment.
Telemedicine Disclosure
This prescription may be issued through telemedicine. If you experience concerning symptoms or severe reactions, contact your prescribing clinician immediately or seek emergency medical care.
Disclaimer
This summary does not include all information about this compounded medication and should not replace medical advice from your healthcare provider or pharmacist. Always consult your provider for complete safety information, potential interactions, and individualized recommendations. This compounded medication has not been evaluated or approved by the FDA for safety or efficacy. Patients are encouraged to report negative side effects of prescription drugs to the FDA MedWatch program or by calling 1-800-FDA-1088.
